Fer-de-Lance⁵ (1934)
APA: Point of Death (1934) [American Magazine]
APA: Meet Nero Wolfe (194?)

The League of Frightened Men^{1, 2} (1935)
APA: Frightened Men

The Rubber Band⁴ (1936)
APA: To Kill Again (1960)

The Red Box¹ (1937)

Too Many Cooks⁶ (1938)

Some Buried Caesar³ (1939)
APA: The Red Bull (1945) [condensed version]

Over My Dead Body (1940)

Where There’s a Will (1940)
APA: Sisters in Trouble

Black Orchids¹¹ (1942)
includes novellas:
Black Orchids
Cordially Invited to Meet Death [APA: Invitation to Murder (1956)]

Not Quite Dead Enough (1944)
includes novellas:
Not Quite Dead Enough
Booby Trap

The Silent Speaker⁹ (1946)

Too Many Women³ (1947)

And Be a Villain^{2, 9, 11} (1948)
APA: More Deaths Than One¹⁰ (1949)

Trouble in Triplicate³ (1949),
includes novellas:
Before I Die
Help Wanted, Male
Instead of Evidence

The Second Confession^{9, 10} (1949)

Three Doors to Death⁴ (1950)
includes novellas:
Man Alive
Omit Flowers
Door to Death

In the Best Families^{4, 9} (1950)
APA: Even in the Best Families (1951)

Curtains for Three² (1950)
includes novellas:
The Gun with Wings
Bullet for One
Disguise for Murder

Murder by the Book⁵ (1951)

Triple Jeopardy⁶ (1952)
includes novellas:
Home to Roost (APA: Nero Wolfe and the Communist Killer, APA: Nero Wolfe Devises a Strategem)
The Cop-Killer
The Squirt and the Monkey (APA: See No Evil, APA: Dazzle Dan Murder Case)

Prisoner’s Base (1952)
APA: Out Goes She (1955)

The Golden Spiders (1953)

Three Men Out (1954)
includes novellas:
Invitation to Murder (APA: Will to Murder)
The Zero Clue (APA: Scared to Death)
This Won’t Kill You (APA: This Will Kill You, APA: The World Series Murder)

The Black Mountain⁸ (1954)

Before Midnight⁸ (1955)

Three Witnesses⁵ (1956)
includes novellas:
The Next Witness (APA: The Last Witness)
When a Man Murders…
Die Like a Dog (APA: The Body in the Hall, APA: A Dog in the Daytime)

Might as Well Be Dead^{7, 9} (1956)

Three for the Chair (1957)
includes novellas:
A Window for Death (APA: Nero Wolfe and the Vanishing Clue)
Immune to Murder
Too Many Detectives

If Death Ever Slept^{8, 9} (1957)

And Four To Go (1958)
APA: Crime and Again (1959), includes novellas:
Christmas Party (APA: The Christmas Party Murder)
Easter Parade
Fourth of July Picnic (APA: Fourth of July Murder, APA: Labor Union Murder)
Murder Is No Joke

Champagne for One¹¹ (1958)

Plot It Yourself⁶ (1959)
APA: Murder in Style (1960)

Three at Wolfe’s Door⁹ (1960)
includes novellas:
Poison a la Carte
Method Three for Murder
The Rodeo Murder (APA: The Penthouse Murder)

Too Many Clients⁷ (1960)

The Final Deduction⁷ (1961)

Gambit⁹ (1962)

Homicide Trinity (1962)
includes novellas:
Eeny Meeny Murder Mo
Death of a Demon (APA: The Gun Puzzle)
Counterfeit for Murder (APA: The Counterfeiter’s Knife)

The Mother Hunt (1963)

Trio for Blunt Instruments (1964)
includes novellas:
Kill Now — Pay Later
Murder Is Corny
Blood Will Tell

A Right To Die (1964)

The Doorbell Rang¹⁰ (1965)
Finalist 1966 Gold Dagger Award

Death of a Doxy (1966)

The Father Hunt (1968)

Death of a Dude (1969)

Please Pass the Guilt⁹ (1973)

A Family Affair⁹ (1975)

Death Times Three (1985)
includes novellas:
Bitter End¹² (1940)
Frame-Up for Murder¹³ (1958)
Assault on a Brownstone¹⁴ (1961)

Double for Death (1939)

Bad for Business (1940)

The Broken Vase (1941)

Under the Andes (1914) [1985]

How Like a God (1929)

Seed on the Wind (1930)

Forest Fire (1933)

The President Vanishes (1934) [published anonymously, reprinted under real name in 1967]

The Hand in the Glove: A Dol Bonner Mystery (1937)
APA: Crime on Her Hands (1939)

Mountain Cat (1939)
APA: The Mountain Cat Murders (1943)

Red Threads (1939) [Inspector Cramer]

Alphabet Hicks (1941)
APA: The Sound of Murder (1965)

A Prize for Princes (1964)

Justice Ends at Home and Other Stories (1977) [SS]

An Officer and a Lady & Other Stories (2000) [SS]

Her Forbidden Knight (1997)